a Formula for deriving Acute HHBP for Children = [aPAD (mg/kg/day) x 1000 (µg/mg)] / [0.15 (L/kg-day) Drinking Water Intake-Body Weight (DWI-BW) ratio]; Formula for deriving Acute HHBP for Females 13-49 Years = [aPAD (mg/kg/day) x 1000 (µg/mg)] / 0.0354 (L/kg/day) DWI-BW ratio
b Formula for deriving Chronic HHBP for General Population = [cPAD (mg/kg bw/day) x 1000 (µg/mg) x 0.2 RSC ] / 0.0338 (L/kg/day) DWI-BW ratio; Formula for deriving Chronic HHBP for Females 13-49 Years = [cPAD (mg/kg bw/day) x 1000 (µg/mg) x 0.2 RSC ] / 0.0354 (L/kg/day) DWI-BW ratio, and RSC = Relative Source Contribution assumed as 20%
c Where there is no value, refer to the document for the cancer classification and quantification.
d No value denotes that carcinogenic quantification is not applicable and therefore, no carcinogenic HHBP is determined.
e Formula for deriving carcinogenic HHBP (ppb) = [10-6 or 10-4/Drinking Water Unit Risk (ppb-1), where Drinking Water Unit Risk (ppb-1) = [CSF (per mg/kg/day) x 0.0338 (L/kg/day) adult DWI-BW ratio]/[1000 (µg/mg)]
f Represents the lowest benchmarks for the lifestage/population evaluated.
g Pesticide has no current registrations for food-use
h Pesticide is now classified as non-food use; benchmarks are based on tox data from 2017 HHBP update, using 2021 updated exposure factors.
i Pesticide was reevaluated by OPP with updated exposure pattern information demonstrating that no effects were seen at doses relevant for human health risk assessment; benchmarks were derived from 2017 OPP toxicity values using updated 2021 exposure factors.
j Mancozeb’s cancer risk is calculated by estimating exposure to mancozeb-derived ETU and using the ETU cancer potency factor (Q1*) of 6.01 x 10 -2 (mg/kg/day)-1